Triptorelin (GnRH) 2mg

$42.00

Triptorelin 2mg is the synthetic stability-modified decapeptide analog of native GnRH with a D-tryptophan substitution at position 6 that blocks the primary enzymatic cleavage site. Greater than 99 percent HPLC verified for in-vitro HPG-axis research.

100 in stock

Description

Buy Triptorelin (GnRH) 2mg – Peptide Science

Triptorelin (GnRH) 2mg Overview

Triptorelin 2mg from Peptide Science is the synthetic stability-modified decapeptide analog of native gonadotropin-releasing hormone (GnRH), supplied as a lyophilised vial for in-vitro and preclinical HPG-axis research. The compound differs from native GnRH by a D-tryptophan substitution at position 6, which extends the in-vitro half-life by reducing enzymatic degradation.

Compound Class and Mechanism

Triptorelin has the sequence pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2, with the position-6 D-tryptophan substitution replacing the native glycine. The D-amino-acid substitution blocks the primary enzymatic cleavage site between residues 6 and 7 used by GnRH-degrading endopeptidases, giving the analog substantially longer in-vitro half-life than the native gonadorelin sequence. The peptide retains full binding affinity at the GnRH receptor and produces sustained activation followed by receptor desensitisation in extended cell-culture protocols. Browse the broader sexual-health peptide range.

Specifications

Property Value
Compound Triptorelin (sequence pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2)
Class Stability-modified GnRH analog; D-Trp(6) GnRH-receptor agonist
Amino-acid count 10
Molecular weight approximately 1311 g/mol
Supplied form Lyophilised powder, sealed vial
Strength 2 mg per vial
Purity greater than 99 percent (HPLC verified)
Storage 2 to 8 degrees Celsius lyophilised; minus 20 degrees Celsius long-term

For the native unmodified GnRH decapeptide, see Gonadorelin 10mg.

Reconstitution and Handling

The lyophilised vial reconstitutes with bacteriostatic water at the working concentration set by the principal investigator. Aliquoting reconstituted stock for single-use frozen storage is the standard preclinical handling practice cited in peptide-research literature.

Quality and Shipping

Each batch passes HPLC at greater than 99 percent purity, with mass-spectrometry identity confirmation. A Certificate of Analysis accompanies every order. Material is filled in a US laboratory under ISO 9001:2015-aligned quality systems and dispatched in temperature-monitored insulated packaging via overnight or two-day courier.

For laboratory research and development use only. Not for human or veterinary consumption. Has not been evaluated by the U.S. Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Purchasers acknowledge they are qualified researchers age 21 or older and accept responsibility for compliance with all applicable federal, state, and local laws.

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